https://www.ceesdekker.net Secrets

https://www.ceesdekker.net Secrets

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Employing single-molecule optical and AFM imaging and drive-spectroscopy procedures, we request to unravel the mechanistic facets of the construction and dynamics of chromosomes. Our research pursuits contain:

It absolutely was only inside the nineteen nineties however, when nanotechnology experienced Superior to the degree wherever single molecules may be manipulated, that the first experimental units commenced to appear.

[Laughs] ‘It had been absolutely an incredible possibility! At enough time, I used to be effectively conscious that it could go Improper and that I could become significantly less prosperous, but I just overlooked that. Curiosity has often been my strongest driving power. And luckily everything labored out.’

Due to the fact 2000, Dekker has shifted the primary target of his work in the direction of biophysics in which he scientific tests the Homes of single biomolecules and cells using the resources of nanotechnology. This modification of industry was driven by his fascination for your extraordinary functioning of biological molecular structures, and also via the long-phrase viewpoint a large number of appealing discoveries can be expected On this discipline.[5] Recent traces of exploration in his biophysics team are in the areas of:[6]

2012, discovery that nucleoid occlusion underlies the precision of bacterial cell division; and to start with ever analyze on the dynamics DNA supercoils and the discovery of supercoil hopping

Direct immobilization of indigenous yeast iso-1 cytochrome c on bare gold: speedy electron relay to redox enzymes and zeptomole protein-film voltammetry

Considering the fact that 2000 he moved to solitary-molecule biophysics and nanobiology, with analysis from DNA supercoiling research of nucleosomes and DNA repair proteins to DNA translocation as a result of nanopores. Not long ago his analysis has focused on finding out cell division with bacteria on chip, when his final interest is during the route of recognizing artificial cells.

Atomic power microscopy reveals that vaccinia topoisomerase IB generates filaments on DNA within a cooperative vogue

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‘The fantastically subtle way wherein factors in mother nature operate never ceases to amaze me. If we clear up the puzzle of how lifestyle arrived into becoming, I be expecting that my amazement on the complexity of generation can have amplified and with it my awe to the greatness of your Creator.’

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2001, discovery of solitary-electron transistors at area temperature based upon nanotubes; realization of to start with logic circuits with carbon nanotube equipment; and discovery of your molecular composition of DNA repair enzymes with AFM

Allow’s 1st glance back again at this time when you decided to shift your target from superconductivity and nanotubes to biology at the end of the nineties.

The biophysicist from Delft – who has actually been Among the most cited researchers inside the Netherlands For many years cees dekker – requires his responsibility to add on the explanation and popularisation of his work within the border of physics and biology particularly significantly and frequently seems while in the media; if not to talk about his get the job done, then about the relationship in between science and his Christian faith.