The Single Best Strategy To Use For ceesdekker.net
The Single Best Strategy To Use For ceesdekker.net
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Nanotechnology features a range of options to lead to biology. Right here I'll existing illustrations exactly where nanofabrication – the opportunity to make confined constructions with Proportions at will – is made use of to look at the biophysics of single molecules and cells. I'll present some examples from our lab:
You regularly get entangled in discussions about science and religion. You might have also created quite a few textbooks on the topic. Don’t you imagine that sooner or later We're going to know every little thing Which God’s function are going to be above?
[Laughs] ‘It absolutely was unquestionably an awesome hazard! At some time, I used to be properly mindful that it could go Improper and that I could turn out to be much less successful, but I just disregarded that. Curiosity has normally been my strongest driving pressure. And luckily everything labored out.’
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
2010, made a new way (‘wedging transfer’) to manipulate nanostructures; very first report of DNA translocation by graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into good-state nanopores
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en fulfilled 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We use nanofabricated microfluidic structures to sample spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which evaluate the basic part of spatial confinement on the molecular and cellular degree. Our tasks consist of the following:
2011, 1st in vitro measurements of transport across just one biomimetic nuclear pore complicated; improvement of multiplexed magnetic tweezers for kilo-molecule cees dekker experiments; and resolved the system of homology recognition in DNA homologous recombination
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Bulk-floor coupling identifies the mechanistic relationship concerning Min-protein patterns in vivo and in vitro
In 1993 he was appointed as Associate Professor at Delft University of Technological know-how. Inside the mid-nineties Dekker and his workforce accomplished results with the invention in the Digital Attributes of carbon nanotubes, the very first solitary-molecule transistor together with other nanoscience.
‘That issues the artificial cell, as Section of the Dutch BaSyC initiative. Craig Venter appeared best-down in Those people days and determined about 5 hundred genes which can be minimally expected to get a operating mobile. We want to look bottom-up: how can we shift from a number of molecules to an entire biological program?
Visualization of unstained DNA nanostructures with Superior in-concentration transmission electron microscopy procedures
Supercoiling-dependent DNA binding: quantitative modeling and apps to bulk and single-molecule experiments